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2 Anti-Aging Supplements That Help Protect Collagen And Prevent Sagging Skin

November 7, 2025 by Mariam Qayum

 
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If you’re over 40 and noticing the usual signs of aging—skin that seems less firm, sagging around the cheeks or jawline, fine lines creeping in—you’re not alone. Part of what’s happening is your natural collagen production decreasing over time, which leads to skin “slumping” instead of bouncing back. According to experts, while no pill can replace a facelift, certain supplements may support collagen health and reduce sagging when combined with smart skin habits. Here are two top supplements backed by growing evidence.

1. Collagen Peptides

Oral collagen supplements (often labeled as hydrolyzed collagen or collagen peptides) promise to “feed” your skin’s collagen network from the inside. Some double‑blind studies show that taking about 5 g daily for 12 – 16 weeks improved dermal density and reduced wrinkle depth.

However, it’s worth noting that a recent meta‑analysis found no significant benefit in higher‑quality trials, especially those not industry‑funded.

Collagen peptides may help some people, but results can vary. Pairing them with proper diet, sun protection, and lifestyle matters.

2. Vitamin C

Vitamin C is a critical co‑factor for collagen synthesis—it helps skin cells build and stabilize collagen fibers. Studies show that supplementation improved collagen gene expression and reduced oxidative damage in skin fibroblasts. In a recent human trial, combining 80 mg of vitamin C with collagen improved dermal density and skin texture over 16 weeks.

Vitamin C supports your skin’s natural collagen-building machinery. It’s a strong choice to pair with other skin‑health strategies.

If you’re looking to maintain a firmer, more lifted appearance into your 40s and beyond, consider layering strategy: collagen peptides to support structure and vitamin C to aid production. Together, these supplements make a strong “anti‑sagging” team—but remember: they work best when life and skincare habits back them up. Starting early and being consistent will give you the best chance of seeing results.

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