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Stressed Out? A Doctor Suggests Taking These 4 Supplements To Help Ease Anxiety: Magnesium, More

May 14, 2025 by Faith Geiger

 
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There are many ways to lower stress levels and manage anxiety. When worse comes to worst, you may turn to medication—but while options like Xanax can offer fast relief, they also come with risks like dependence and drowsiness. Psychiatrist Dr. Amen, a.k.a. @docamen on TikTok, suggests that certain supplements could be a good, gentler first step. He offers four options in particular.

“If you’re feeling anxious, tense, or nervous, I love L-Theanine. I love magnesium, especially magnesium citrate,” he notes. “Love ashwagandha and GABA. These are the things that I use with my patients all the time. Before you reach for a benzo like Xanax, try those first.” Learn more about the benefits of each below.

1. L-Theanine

L-Theanine is one particular supplement that can be a game-changer for those struggling with anxiety. This naturally occurring amino acid is found in green tea—and it's available in supplement form. L-theanine, as noted by Dr. Amen, can bring a sense of calm without sedation. It works by increasing neurotransmitters that play a role in mood, sleep and stress: GABA, serotonin, and dopamine. It's definitely worth a shot if you frequently find yourself on edge.

2. Magnesium

Those viral sleepy girl mocktails had some science behind them! And magnesium isn't just good for sleep; it could do wonders to reduce anxiety levels in your body. This essential mineral plays a role in a wide array of your body's functions, including nervous system regulation. Magnesium citrate, in particular, works to relax your muscles, relieve tension, and even help you catch some Z's with ease.

3. Ashwagandha

Ashwagandha has gotten a lot of buzz in the wellness world over the past few years, and for good reason. It isn't just a passing trend; this adaptogenic herb has been used in Ayurvedic medicine for centuries. It can be a simple but powerful tool to reduce cortisol levels, manage stress, and help you find a sense of calm.

4. GABA

GABA is a neurotransmitter that's crucial to your body's ability to relax, as it blocks nerve impulses in your brain. Sometimes it can be helpful to take a GABA supplement to mimic your brain's natural GABA for a calming effect. This is an especially good option when you are experiencing peak anxiety levels and need an extra boost of peace.

Bottom Line

So, there you have it: Xanax isn't the only option! "Before you reach for a benzo like Xanax, try those first," Dr. Amen tells viewers. These natural remedies can support the body’s stress response without many of the potential downsides of prescription medications. Keep in mind, though, that even natural supplements come with risks. When in doubt, talk to your doctor about the best options for your specific needs.

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