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The Potentially Dangerous Supplements That Could Lead To Thyroid Issues, According To Doctors: Calcium, More

January 20, 2026 by Faith Geiger

 
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Today, there are supplements on the market promising just about any result you can think of, from better sleep to increased focus and energy to healthier hair, skin, and nails. And while supplementing with vitamins and minerals can be one great way to keep your health in check if your diet has any nutritional gaps, it’s crucial to remember that all supplements come with potential side effects. In fact, if you don’t practice caution, you could do damage to your hormonal health.

Some supplements could take a toll on your thyroid, in particular, especially when combined with other medications. When it comes to making changes to your supplement routine, knowing the potential risks at hand is crucial. Below, we’re breaking down why it’s important to be cautious when it comes two options: iodine and calcium. Read on for expert insight and information on how to take each one safely.

1. Iodine

Iodine is a trace mineral that’s important for healthy thyroid function, which regulates metabolism, energy levels, and even skin health. In areas where iodine deficiency is common, or for people who don’t get enough iodine in their diets from foods like seafood and dairy, supplements can help prevent thyroid disorders such as hypothyroidism. Ensuring you get enough iodine supports hormonal balance and cognitive function—but you know what they say about too much of a good thing.

Too much iodine can backfire. Excessive iodine intake can disrupt thyroid function, potentially triggering hyperthyroidism or autoimmune thyroid conditions. These hormonal imbalances may lead to symptoms such as weight changes, fatigue, and sometimes, premature aging of the skin. The safe range for iodine is pretty narrow, so it's best to consult with a doctor before adding iodine supplements to your routine.

2. Calcium (when taken with certain medications)

Calcium is an incredibly important mineral that all of our bodies need to function. It keeps our bones, teeth, and muscles strong, and assists our nerve functions. However, before you supplement it, you should double-check with your doctor if that's a safe idea. As it turns out, calcium can cause potentially dangerous reactions when combined with some medications.

"Calcium, when taken too close to certain prescription medications, particularly iron supplements, thyroid hormones like levothyroxine, and some antibiotics, can interfere with how your body absorbs those medications," says pharmacy doctor and the VP of Pharmacy and Medical Operations at EdenDr. Rebecca Emch. "This doesn't mean calcium is 'bad,' but the timing matters. Even something as simple as a morning calcium supplement could unintentionally reduce the effectiveness of a thyroid medication if taken together."

Good to know! Stay safe.

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