When it comes to skincare and anti-aging, what you put into your body can be just as important as what you apply on your skin. Supplements have become a popular way to support healthy aging from the inside out—especially those formulated to boost collagen production. Collagen, a protein that keeps skin firm and elastic, naturally decreases with age, leading to fine lines, wrinkles, and sagging. Fortunately, certain anti-aging supplements can help replenish what’s lost and promote smoother, more youthful-looking skin over time.
Dr. Mamina Turegano, MD—a triple board-certified dermatologist, internist, and dermatopathologist—recently revealed her top three supplement recommendations for women over 40 to support collagen production, improve overall skin health, and even help reverse sun damage. Keep reading to learn all of her expert tips.
1. Heliocare vegan dietary supplements
Heliocare vegan dietary supplements can support skin health over 40 in several key ways, thanks to their unique antioxidant formula. Heliocare supplements contain Polypodium leucotomos extract (PLE), a powerful plant-derived antioxidant that helps protect the skin from free radical damage caused by UV rays.
Dr. Turegano says this choice “uses antioxidants extracted from a fern plant, which help the skin maintain its structure and immune response against sun damage. It literally builds your body’s tolerance to UV rays, preventing sun-damaged skin.”

2. Timeline longevity supplements
As we age, our cells—especially skin cells—produce less energy due to declining mitochondrial function. Urolithin A in Timeline supplements promotes mitophagy, the process of clearing out damaged mitochondria and replacing them with healthy ones.
“This has an ingredient called Urolithin A, which helps clear out old and damaged mitochondria, allowing for the creation of new functional mitochondria, which are needed for cells to be healthy and optimize energy production," she states.

3. BeautyCore Probiotics
BeautyCore Probiotics with Fermented Vitamins offer a holistic approach to skin health, especially for those over 40, by combining gut-friendly probiotics with bioavailable, fermented vitamins that work synergistically to nourish skin from within.
She reveals, “This has probiotics that help with collagen production. Collagen is not only in our skin but also in our joints and vessel wall linings.”


