Once you reach your 40s, your skincare routine isn’t just about maintenance—it’s about actively supporting your skin through one of its most transformative decades. Hormonal shifts, slower cell turnover, and collagen loss all play a role in the visible signs of aging, which is why dermatologists recommend incorporating targeted, proven ingredients into your daily regimen.
Dr. Heather, MD, a board-certified dermatologist and educator, recently shared the five skincare ingredients she considers essential for women over 40, highlighting affordable, effective products that support aging skin at every level. According to her, retinol, glycolic acid, and sunscreen are some of the best choices. Read on to learn more.
1. Retinol
“Number one is a retinol,” she says. “I love this product by RoC—it’s affordable and extremely effective.” Retinol, a vitamin A derivative, is one of the most research-backed ingredients for reducing fine lines, improving texture, and encouraging healthy skin cell turnover.

2. Antioxidants (Vitamin C)
Second on her list? Antioxidants. “I love this one by Revision Skincare—it’s a vitamin C that’s safe for sensitive skin,” Dr. Heather shares. Vitamin C is a powerful antioxidant that helps brighten the complexion, fight free radical damage from environmental stressors, and support collagen production.

3. Ceramide-Based Moisturizers
Next, she stresses the importance of a barrier-repairing moisturizer. “I love ceramide-based moisturizers like this one because they help to restore the barrier,” she says. As we age, our skin barrier weakens, leading to dryness and sensitivity—making replenishing lipids like ceramides critical to maintaining healthy skin.

4. Glycolic Acid
For gentle but effective exfoliation, glycolic acid takes the fourth spot. “Love this product by Dr. Dennis Gross—it’s a peel pad you can do at home,” says Dr. Heather. Glycolic acid, an alpha hydroxy acid (AHA), dissolves dead skin cells and boosts radiance while helping to reduce the appearance of fine lines.

5. Sunscreen
And finally, no routine is complete without daily broad-spectrum SPF. “Of course, sunscreen—I love this one by Ilia,” she says, emphasizing that protecting the skin from UV damage is a non-negotiable at any age, but especially after 40, when damage becomes more visible.
By focusing on these five dermatologist-approved ingredients—retinol, vitamin C, ceramides, glycolic acid, and sunscreen—women over 40 can create a simple yet powerful routine that addresses the most common signs of aging head-on. As Dr. Heather puts it: “These products are extremely effective and can make a real difference in the look and feel of your skin.”


