When it comes to supplements, many people assume that because they’re “natural,” they must also be safe. But doctors caution that certain popular supplements may actually carry serious health risks—especially when it comes to blood clotting. While some can interfere with circulation, others may increase the likelihood of dangerous clots forming, which could raise the risk of heart attack, stroke, or other complications. To help you make safer choices, we asked experts to break down three supplements you’ll want to approach with caution if blood clotting is a concern.
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1. Vitamin K
On one hand, Vitamin K is essential for several of factors of your health, including the fact that it plays a crucial role in blood clotting, making it essential for wound healing. However, excessive intake of Vitamin K supplements can increase the risk of blood clots—especially if you have preexisting cardiovascular conditions.
"Vitamin K is essential for blood clotting, which is why it’s often used to counteract blood thinners. However, excessive vitamin K intake—especially from supplements—can thicken the blood and increase clot risk," Dr. Mario Padron, a physician and health expert, warns. This is especially concerning for anyone taking anticoagulant medications like warfarin, as high vitamin K levels can make these drugs less effective. Whenever possible, get your vitamin K from the foods you eat, like leafy greens, rather than supplements.
2. Iron Supplements
Just as with Vitamin K, iron is undeniably essential to your wellbeing. It's necessary for red blood cell production, but too much of it can contribute to clot formation. "High iron levels can promote oxidative stress, inflammation, and increased platelet aggregation—all of which make blood more prone to clotting," explains Dr. Padron. Unless your doctor diagnoses you with an iron deficiency, it's best to get iron from your diet. Reach for lean meats, legumes, and spinach, rather than a high-dose supplement.
3. Red Yeast Rice
Here's one you may not have heard of. Red yeast rice is seen as a natural alternative to statins, targeting high cholesterol levels—but it comes with potential risks, Dr. Padron warns. "Often used as a natural alternative to statins, red yeast rice contains monacolin K, which mimics the cholesterol-lowering effects of prescription drugs. However, in some people, it can lead to increased clot risk by altering blood lipid levels and causing unpredictable coagulation effects." He recommends talking to your doctor about safer ways to manage your cholesterol.
