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Health

Doctors Warn These 4 Supplements Could Be Spiking Your Blood Sugar

October 19, 2025 by Mariam Qayum
shefinds | Health
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Managing blood sugar levels is crucial for overall health, especially for individuals with diabetes or those at risk. While some supplements are marketed to support blood sugar control, certain ones may inadvertently cause blood sugar spikes. Understanding which supplements to approach with caution can help prevent unwanted health complications. Read on to discover four supplements you should stay away from if you’re concerned about spiking your blood sugar levels.

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1. Niacin (Vitamin B3)

Niacin, or nicotinic acid, is commonly used to manage cholesterol levels. However, it can also raise blood glucose levels. According to ColumbiaDoctors, niacin can increase blood sugar by affecting insulin sensitivity, potentially leading to hyperglycemia, especially in individuals with diabetes.

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2. Ginkgo Biloba

Ginkgo biloba is often taken for cognitive enhancement and memory support. However, it may interfere with blood sugar regulation. A study highlighted by GoodRx found that ginkgo biloba could raise blood glucose levels in people taking oral diabetes medications by potentially causing the liver to break down insulin more rapidly.

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3. St. John’s Wort

St. John's Wort is primarily used for mood disorders and depression. However, it can interact with diabetes medications, rendering them less effective. Research from diaTribe.org indicates that St. John's Wort may cause a buildup of metformin in the body, leading to increased insulin release and potential blood sugar fluctuations.

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4. Aloe Vera

Aloe vera is known for its soothing properties and is used in various health supplements. While it may offer benefits for skin and digestive health, aloe vera can lower blood sugar levels. According to Encompass Health, aloe vera may enhance the effects of diabetes medications, potentially leading to hypoglycemia if not monitored closely.

Conclusion

While supplements can offer health benefits, it's essential to be aware of their potential effects on blood sugar levels. Niacin, ginkgo biloba, St. John's Wort, and aloe vera are among the supplements that may cause blood sugar spikes or interfere with diabetes medications. Always consult with a healthcare provider before starting any new supplement regimen, especially if you have diabetes or are at risk, to ensure they are safe and appropriate for your health needs.

Author:

Editorial Assistant

Mariam is an Editorial Assistant and writer at SheFinds, covering everything from style and beauty to health and wellness. Splitting her time between New York and Philadelphia, she brings a sharp eye for trends and a passion for storytelling to the digital space. With a strong editorial background, she’s always exploring the latest in fashion, skincare, and wellness. When she’s not writing or pitching, you’ll find her in the kitchen experimenting with new recipes or planning her next travel adventure. You can reach Mariam at mariam@shefinds.com.

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Older woman taking dietary supplements with water.
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Handful of assorted dietary supplements in palm.
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Pouring supplement powder into a glass of water.
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Woman drinking coffee to combat extreme fatigue.
Grocery store aisle with sugar and sweeteners.
Person having a lunch meal.
Close-up of steaming spearmint tea with fresh leaves
Frustrated older woman touching her head in distress
Woman experiencing chest pain, seeking medical attention
Variety of different types of bread on a table.
Woman holding her head in distress or pain.
Woman experiencing joint pain while sitting down.
Assorted drinks from Dunkin', Chick-fil-A, and Starbucks.
Woman adding sugar to a cup of aromatic coffee.
Wooden board with bagels, blueberries, and butter.
Pouring vitamin D into palm for healthy skin benefits.
Comparing cooking spray and olive oil in a kitchen.
Older woman taking dietary supplements with water.
Brazilian dish featuring rice, beans, and chicken.
Handful of assorted dietary supplements in palm.
Person checking the time while enjoying breakfast.
Pouring supplement powder into a glass of water.
Woman performing yoga on a mat in a studio
Woman drinking coffee to combat extreme fatigue.