Health

4 Potentially Dangerous Supplements That May Be Damaging Your Kidney Health, According To Experts: Comfrey, More

September 6, 2025 by Faith Geiger
shefinds | Health
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Supplements are often marketed as an easy way to give your health a boost. And while they can certainly be helpful in many cases, caution is crucial. Many supplements are ineffective—and some are downright dangerous. Certain options can be especially harmful to your organs. Your kidney, in particular, could be at risk if you’re not careful.

To shed some light on a few potentially dangerous options to steer clear of if you want to keep your kidneys in top shape, we spoke to Dr. Rimas Geiga. He warns against comfrey, licorice root, cascarda sagrada, and ephedra. Learn more about the risks of each below.

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comfrey

1. Comfrey

Comfrey contains pyrrolizidine alkaloids that are toxic to the liver and can also harm the kidneys. Dr. Geiga explains, "Prolonged use or high doses of comfrey can lead to liver damage and kidney toxicity." Instead of comfrey, explore alternatives like chamomile or calendula, which offer soothing properties without the risk of liver or kidney harm.

licorice root supplement

2. Licorice Root

Licorice root, if consumed in large amounts or over extended periods, can cause potassium depletion and elevate blood pressure. This can potentially lead to kidney damage or worsening existing kidney conditions. "Licorice root can be harmful to kidney health due to its effect on potassium levels and blood pressure," warns Dr. Geiga. For digestive health, consider alternatives like chamomile or fennel tea, which can soothe the stomach without the risks associated with licorice root.

cascara sagrada supplement

3. Cascara Sagrada

Often used as a laxative, Cascara sagrada can lead to health issues with prolonged or excessive use, straining the kidneys over time. Dr. Geiga notes, "Excessive use of Cascara sagrada can compromise kidney health due to dehydration and electrolyte imbalances." To support regularity without compromising kidney health, choose gentler laxatives like psyllium husk or incorporate fiber-rich foods into your diet.

ephedrine

4. Ephedra

Ephedra, commonly used for weight loss and energy enhancement, contains ephedrine alkaloids that can elevate blood pressure and increase the risk of kidney damage, especially in individuals with pre-existing kidney conditions or hypertension.

Dr. Geiga warns, "Ephedra can be particularly harmful to those with existing kidney issues." It can also harm your heart, among other risks. For safer energy support, consider guarana, or consult with a healthcare provider for personalized recommendations.

woman in supplement aisle

Bottom Line

All in all, it's crucial to be mindful of everything you're putting into your body—even if you find it at the health store. While supplements can often be a good way to keep your wellbeing in check, speaking to your doctor, paying attention to dosages, and being extremely cautious of potentially harmful options like these is all crucial to staying safe and healthy.

Author:

Freelance Writer

Faith Geiger is a New York-based writer and editor. When she's not covering the latest in health and wellness for SheFinds, she spends her time watching reality TV with her roommates, browsing used bookstores, and enjoying live music. You can reach Faith at [email protected].

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