A Pharmacist Breaks Down 5 ‘Skin-Loving’ Supplements That Are ‘Backed By Science’ And ‘Support’ A Youthful Glow

June 21, 2025 by Lisa Cupido

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Walk into any pharmacy or scroll through TikTok, and you’ll see just how popular supplements have become. With endless options promising everything from better sleep to glowing skin, it’s easy to feel overwhelmed and unsure of what your body actually needs. If your goal is healthier, more youthful-looking skin, the right supplements can support that, but choosing wisely is key.

It’s important to remember that no supplement can replace a nutrient-rich diet. Whole foods remain the best and most effective way to nourish your skin from the inside out. That said, supplements can be a helpful way to fill in nutritional gaps, especially if certain vitamins or minerals are missing from your everyday meals. To help you make better choices, here are five that are particularly beneficial for skin health—and that can help your complexion look more vibrant and well-nourished.

1. Magnesium

Magnesium helps regulate stress hormones, which can reduce inflammation and prevent stress-related breakouts or dullness. It also supports healthy sleep, and better rest gives your skin more time to repair and regenerate overnight. On a cellular level, magnesium contributes to hydration and barrier function — this means it helps your skin retain moisture and stay smooth and hydrated.

2. Probiotics

Your gut health and skin health are more connected than you might think, and probiotics help keep that connection strong. These good-for-you bacteria support a balanced gut microbiome, which can reduce systemic inflammation and skin issues like acne, rosacea, or eczema. When your digestion and nutrient absorption improve, so does your skin’s ability to heal and stay clear.

3. Vitamin D

Vitamin D is essential for skin cell growth and repair. If you are concerned you may have a vitamin D deficiency, it’s worth talking to your doctor about to see if a supplement could benefit you. Supporting your body with enough vitamin D can lead to a more even skin tone, stronger barrier function, and a healthier, more radiant appearance overall.

4. Omega-3 Fatty Acids

Omega-3s, commonly found in fish oil or algae-based supplements, are known for their anti-inflammatory properties and ability to support skin hydration. These healthy fats help maintain the skin’s lipid barrier, which keeps moisture in and irritants out. They also help reduce redness and sensitivity, making your skin look calmer.

5. Zinc

Zinc is a mineral that plays a crucial role in skin repair and inflammation control. It helps heal wounds, fight off acne-causing bacteria, and regulate oil production, which means making sure you have enough zinc in your diet can contribute to a clearer, smoother complexion. Zinc also acts as an antioxidant, protecting skin cells from damage caused by environmental stressors like pollution and UV exposure.

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