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6 Popular Supplements That Can Cause Unexpected Heart Problems, According To Doctors

March 19, 2025 by Faith Geiger
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Supplements are often believed to be a great, simple way to give your health a boost. Whether you want to shed pounds, sleep better, or reduce anxiety, there’s probably a supplement on the market targeting your specific needs. But while supplements can be helpful to your health in many cases, it’s important to keep in mind that they can also come with a range of downsides. This is especially true when it comes to your heart health.

Unfortunately, a lot of options out there could be detrimental to your health, posing a number of risks. To learn about a few of the most potentially dangerous options, we spoke to health expert Dr. Michael Lahey. He warned about six specific supplements, including St. John’s Wort, calcium, and more. Find all of his expert insight below.

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st johns wort

1. St. John’s Wort

St. John’s Wort is an herbal supplement often used as a natural remedy for depression, but it can be risky for those with heart conditions. Dr. Lahey tells us it can be especially dangerous when combined with certain medications. "The supplement should not be used if you take medicines that control heart health because it can cause dangerous interactions with blood thinners or statins," he warns. He recommends talking to your doctor about alternative options to find safer ways to manage mood and mental health without risking harmful interactions.

ephedrine

2. Ephedra

Ephedra, once a popular supplement for weight loss, was banned by the federal government in 2000 due to its dangerous side effects. "Ephedra can produce a spike in blood pressure, and increase the risk of heart attacks or abnormal heart rhythms," Dr. Lahey warns. Although it's been banned in the United States, supplements containing ephedra might still be available on some shelves. When it comes to weight loss, your best bet is to stick to tried and true methods—like regular exercises and a healthy diet—rather than turning to supplements.

bitter orange

3. Bitter Orange

Bitter orange is another ingredient found in many weight loss supplements. Like ephedra and other stimulants, it can do a number on your heart. According to Dr. Lahey, "this stimulant is dangerous by raising blood pressure and causing irregular heartbeats, which are dangerous to heart patients in the elderly." If you're trying to shed pounds, he emphasizes that a "safe weight loss plan involves fiber intake and engaging in physical exercises." Noted!

yohimbe

4. Yohimbe

Unfortunately, many supplements promising weight loss can be a nightmare for your heart. Yohimbe is one that has gained popularity as a fat burner and a supplement for enhancing sexual performance. However, Dr. Lahey warns against it, especially if you want to keep your heart health in good shape. "Side effects include an increase in pulse rate and blood pressure—not a plus for any person with heart problems, especially those who are more than fifty years old," he cautions. Instead of turning to Yohimbe, he recommends focusing on "lifestyle modifications to enhance cardiovascular functioning," such as a balanced diet and regular exercise.

vitamin e

5. Vitamin E

Vitamin E is known for its antioxidant properties, which can certainly be helpful for your health. However, Dr. Lahey warns that taking it in large doses can be dangerous. "Large doses of vitamin E, greater than 400 international units a day, have been associated with hemorrhagic stroke and heart failure," he tells us. He emphasizes that it’s better to get vitamin E from whole foods rather than supplements. "I suggest you obtain your dose of vitamin E from foods such as nuts and seeds, spinach, and such like," he suggests. Got it!

calcium supplements

6. Calcium Supplements

Calcium is undoubtedly essential. It famously plays a central role, for example, in maintaining strong bones. But when it comes to calcium supplements, caution is key. Dr. Lahey warns that "supplementing with calcium regularly can lead to hardening of arteries and heart disease." Instead of relying on calcium pills, he suggests turning to natural sources, such as "green vegetables and dairy products," which provide calcium without the associated cardiovascular risks. These dietary sources are not only safer but also provide a range of other nutrients that support overall health. Perfect!

Author:

Freelance Writer

Faith Geiger is a New York-based writer and editor. When she's not covering the latest in health and wellness for SheFinds, she spends her time watching reality TV with her roommates, browsing used bookstores, and enjoying live music. You can reach Faith at faithkgeiger@gmail.com.

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Ariana Grande at the Golden Globes red carpet.
Kylie Jenner showcasing style at the Met Gala 2025.
Image from SHEfinds
Taylor Swift and Travis Kelce at a public appearance.
Kim Kardashian's controversial Capri leggings and oversized shirt outfit.
Ivanka Trump and Jared Kushner at a social event.
Brad Pitt and Ines de Ramon at the F1 premiere.
Bad Bunny performing or attending the Grammys.
Madonna's blue mini dress and metallic boots criticized by fans.
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