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Doctors Say Women Over 50 Should Use Caution With These 5 Supplements During Menopause: DHEA, More

September 4, 2026 by Mariam Qayum
shefinds | Food
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Menopause can bring a host of changes, from hot flashes and sleep problems to shifts in mood, energy and bone health. As a result, many women turn to supplements marketed as natural ways to balance hormones and ease symptoms. But experts warn that “natural” doesn’t always mean risk-free, and certain supplements may cause unwanted side effects, interact with medications or affect hormone levels when taken without proper guidance.

For women over 50, doctors say it’s especially important to look beyond the promises on supplement labels and consider whether a product is actually appropriate for their individual needs. From hormone-focused supplements to commonly used vitamins and minerals, here are five that women going through menopause may want to approach with caution and discuss with a healthcare professional before adding to their routine.

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1. Vitamin D

Vitamin D is one of the most common and popular supplements out there, especially because it's something you can't get from food, and many people find that they need to supplement it as they get older to prevent and ease symptoms or conditions like osteoporosis. However, menopausal women are urged to take caution before taking it.

"Vitamin D should be carefully dosed during the menopausal years because moderate amounts support strong bones, but high doses can increase the amount of calcium in the blood and create an imbalance that will disrupt hormone signaling and can manifest as fatigue, irritation, or disrupted sleep patterns instead of relief from menopause symptoms," says general practitioner Dr. Maria Knobel.

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2. Black Cohosh

Some people may not be familiar with black cohosh, a supplement derived from a flowering plant that has been studied for its potential effects on estrogen-related pathways, which could make it appealing to women experiencing menopause.

Still, some health experts believe the inconsistent research and results of the supplement should serve as a warning.

"Black Cohosh is used in many of the menopause blends that are available," explains Dr. Knobel. "But black cohosh does not have consistent results for most women. Black cohosh can influence how a woman's body responds to estrogen receptors, which can cause menopause symptoms to be unpredictable and difficult to read, especially during hot flashes at night or mood changes."

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3. Ginseng

Ginseng is a supplement that is trending more these days, especially in the holistic medicine world. It is said to help boost energy levels, increase brain function and immune support, and even help people manage their stress levels. However, Dr. Knobel says it can create instability hormone-wise.

"Another supplement that can create an unstable environment is Ginseng," she notes. "Ginseng affects the stress hormone cortisol; high levels of cortisol can also block progesterone function."

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4. Magnesium

Magnesium is another popular supplement among women in menopause, particularly because it is often promoted for sleep, muscle function and relaxation. While magnesium is an essential mineral, taking more than your body needs does not necessarily provide additional benefits and can cause side effects.

High doses of magnesium from supplements can lead to diarrhea, nausea and abdominal cramping. Women with kidney problems should be particularly cautious because their bodies may have difficulty clearing excess magnesium.

Rather than assuming more is better, women should consider whether they actually need supplementation and discuss the appropriate dose with a healthcare professional, particularly if they take medications or have an underlying health condition.

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5. DHEA

DHEA is a hormone naturally produced by the body that can be converted into both estrogen and testosterone. It is sometimes marketed as a supplement for women experiencing menopause-related changes in sexual health, energy and overall well-being.

However, because DHEA can affect hormone levels, it isn't something women should casually add to their routine without medical guidance. Potential side effects can include acne, oily skin, unwanted hair growth and changes in mood, while its effects can vary significantly from person to person.

Women considering DHEA should speak with their doctor before taking it, particularly if they have a hormone-sensitive condition or are already using hormone therapy.

 

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Editorial Assistant

Mariam is an Editorial Assistant and writer at SheFinds, covering everything from style and beauty to health and wellness. Splitting her time between New York and Philadelphia, she brings a sharp eye for trends and a passion for storytelling to the digital space. With a strong editorial background, she’s always exploring the latest in fashion, skincare, and wellness. When she’s not writing or pitching, you’ll find her in the kitchen experimenting with new recipes or planning her next travel adventure. You can reach Mariam at mariam@shefinds.com.

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