Skip to main content
Modern workspace with a person typing on a laptop.
Chic haircuts for women over 50 trending in 2026.
Donald Trump discussing maternal healthcare at a public event.

Celebrity

Amy Schumer Reveals She Lost 30-Lbs 'So Quick' On Weight Loss Medication, But Had A 'Horrible Experience' With Nausea: 'What's The Point?'

February 3, 2025 by Marissa Matozzo
shefinds | Celebrity
Featured image

Amy Schumer has openly admitted to using Ozempic before, and received praise from fans for her honesty about her weight loss journey in recent years. The comedian, 43, also just elaborated on her experience with weight loss drugs, and it was unpleasant, to say the least. The I Feel Pretty star explained that she had a bad reaction to the drug, possibly due to her genetic makeup.

During her interview on The Howard Stern Show last week, Schumer said: “I have this gene, GDF15, which makes you extremely prone to nausea, which is why I was so sick during my pregnancy.” She continued: “So, I tried Ozempic almost three years ago and I was, like, bedridden. I was like, vomiting—and then you have no energy.”

 

house unit img
Women Are Swapping Their Boring Water For This Ice Pop Electrolyte Mix!
Amy Schumer leaving SiriusXM Radio in New York City.

Amy Schumer Reveals She Dropped 30 Lbs Fast on Weight Loss Medication but Struggled With ‘Horrible’ Nausea: ‘What’s the Point?’

The Trainwreck alum recalled "shriveling away" and suffering from nausea after taking the medication. "I lost 30 pounds so quick. I looked great, but I couldn’t lift my head off the pillow. So, what’s the point?" Schumer explained. The mom of one (who shares son Gene, 5, with husband Chris Fischer) memorably opened up about her Ozempic drawbacks on a 2023 episode of Watch What Happens Live with Andy Cohen, mentioning that she couldn't continue using the drug because of its side effects.

The Life & Beth actress said: "I was one of those people that felt so sick and couldn’t play with my son. I was so skinny and he’s throwing a ball at me and [I couldn’t]." Schumer continued: "But I immediately invested [in it] because I knew everyone was going to try it."

Amy Schumer at the 2024 Power of Women event.

Schumer also previously discussed her liposuction procedure on Chelsea Handler's podcast Dear Chelsea in 2022, telling the host: "I got liposuction. I never thought that I was going to do anything like that. Like when I would hear liposuction I was just like, that's so crazy to me, and I would say that I'm not ever going to do anything...Cut to turning 40 after having a C-section!"

The combination of endometriosis and multiple surgeries led Schumer to decide to go ahead with the procedure. As she recalled: "I got lipo and I'm feeling really good...I just wanted to say that, because if anybody sees me in pictures or anything and they're like, she looks thinner, and whatever: it's because I had a surgery. It's too hard, and I just want to be real about it."

Amy Schumer at the New York premiere of IF at SVA Theater.

 

Amy Schumer Slams Celebs Who 'Lie' About Ozempic Use On The Howard Stern Show 

Schumer, who was previously diagnosed with Cushing Syndrome, also took a moment to call out A-listers who "lie" about Ozempic use during her recent chat with Howard Stern. "Everyone has been lying saying, ‘Oh smaller portions.’ Like shut the f-ck up," she said.

 

 

 

She went on: "You are on Ozempic or one of those things or you got work done. Just stop. Be real with the people. When I got lipo, I said I got lipo."

Despite experiencing adverse effects from the medication, the Kinda Pregnant star emphasized that the drug has been beneficial for many others. "Other people take it and they’re all good. So, God bless them," she said.   

Author:

Former Senior Staff Writer

Marissa is a Brooklyn-based journalist and former senior staff writer at SheFinds, specializing in pop culture, entertainment, and lifestyle topics. She crafted engaging, SEO-driven content on celebrity style, entertainment news, beauty trends, and wellness. Her work, including red carpet coverage and features on fashion, music, film, and NYC culture, has appeared in PAPER Magazine, Paste Magazine, The Knockturnal, Bandsintown, and more. When not writing, you can find her with her nose in a great book, at an indie concert, vintage shopping or visiting the best coffeeshops in NYC.

Madonna at the Met Gala in a stunning outfit.
Taylor Swift arriving in a private jet in 2024.
Jennifer Lopez in Defaience at the 2025 American Music Awards.
Vittoria Ceretti with Leonardo DiCaprio at a gala.
Emma Stone attending the Annual Actor Awards ceremony.
Salma Hayek at the 12th Annual Breakthrough Prize Ceremony.
Kate Middleton during a state visit looking elegant.
Ariana Grande showcasing her fashion at the Golden Globes.
Kylie Jenner's elegant ensemble at the Met Gala 2025.
Taylor Swift and Travis Kelce enjoying a night out.
Ivanka Trump and Jared Kushner attending a public event.
Brad Pitt and Ines De Ramon at the European premiere.
Bad Bunny's glamorous Grammy moment, celebrating music and style.
Angelina Jolie celebrating at the Trophee Chopard Award ceremony.
Selena Gomez supporting mental health at Rare Impact Benefit.
Brad Pitt and Ines De Ramon at the F1 premiere event.
Queen Camilla with Prince Harry and Meghan Markle at an event.
Travis Kelce and Taylor Swift enjoying a public outing together.
Barack Obama, Michelle Obama, Malia, and Sasha posing for a family photo.
Britney Spears at the 4th Annual Hollywood Beauty Awards event.
Madonna at the Met Gala in a stunning outfit.
Taylor Swift arriving in a private jet in 2024.
Jennifer Lopez in Defaience at the 2025 American Music Awards.
Vittoria Ceretti with Leonardo DiCaprio at a gala.
Emma Stone attending the Annual Actor Awards ceremony.
Salma Hayek at the 12th Annual Breakthrough Prize Ceremony.
Kate Middleton during a state visit looking elegant.
Ariana Grande showcasing her fashion at the Golden Globes.
Kylie Jenner's elegant ensemble at the Met Gala 2025.
Taylor Swift and Travis Kelce enjoying a night out.
Ivanka Trump and Jared Kushner attending a public event.
Brad Pitt and Ines De Ramon at the European premiere.
Bad Bunny's glamorous Grammy moment, celebrating music and style.
Angelina Jolie celebrating at the Trophee Chopard Award ceremony.
Selena Gomez supporting mental health at Rare Impact Benefit.
Brad Pitt and Ines De Ramon at the F1 premiere event.
Queen Camilla with Prince Harry and Meghan Markle at an event.
Travis Kelce and Taylor Swift enjoying a public outing together.
Barack Obama, Michelle Obama, Malia, and Sasha posing for a family photo.
Britney Spears at the 4th Annual Hollywood Beauty Awards event.